Methyl 5-fluoro-1H-indole-2-carboxylate

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5-Fluoro-1H-indole-3-carb­oxy­lic acid

In the title compound, C(9)H(6)FNO(2), the carboxyl group is twisted slightly away from the indole-ring plane [dihedral angle = 7.39 (10)°]. In the crystal, carboxyl inversion dimers linked by pairs of O-H⋯O hydrogen bonds generate R(2) (2)(8) loops and N-H⋯O hydrogen bonds connect the dimers into (10[Formula: see text]) sheets.

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Methyl 2-(5-fluoro-1H-indol-3-yl)-2-oxoacetate

The indolyl portion of the title mol-ecule, C(11)H(8)FNO(3), is flat, the five- and six-membered rings making a dihedral angle of 0.815 (6)°. Inter-molecular N-H⋯O hydrogen bonds link adjacent mol-ecules into a linear chain. Slipped π-π stacking inter-actions between two neighboring indole groups further consolidate the mol-ecules into a three-dimensional supra-molecular architecture [centroid-...

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Ethyl 5-(4-Bromophenyl)-4-methyl-1H-pyrrole- 2-carboxylate

This note describes a sequence converting an oxime-substituted pyrrolidine into a trisubstituted pyrrole structure. The synthetic route is based on a double chlorination of the pyrrolidine substrate followed by the base induced formation of both an imine and a nitrile oxide functionality. The latter reacts with an immobilized thiourea to yield an isothiocyanate which upon elimination generates ...

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5-Chloro-N′-cyclo­hexyl­idene-3-methyl-1H-indole-2-carbohydrazide

In the title compound, C16H18ClN3O, the cyclo-hexane ring adopts a distorted chair conformation. In the crystal, pairs of mol-ecules are linked by N-H⋯O hydrogen bonds into inversion dimers, forming R 2 (2)(10) ring motifs. These dimers are connected through C-H⋯N hydrogen bonds into chains along the a axis, forming layers parallel to (101).

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5-Methyl-1H-indole-3-carbaldehyde

The title mol-ecule, C(10)H(9)NO, is almost planar with an r.m.s. deviation for all non-H atoms of 0.0115 Å. In the crystal, mol-ecules are connected through N-H⋯O hydrogen bonds into chains running along [021]. The chains are further connected via C-H⋯π inter-actions, forming layers in the bc plane.

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ژورنال

عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online

سال: 2006

ISSN: 1600-5368

DOI: 10.1107/s1600536806031448